Products Description of Madecassic Acid CAS#18449-41-7
Madecassic acid is a pentacyclic triterpene compound of the ursane type, naturally occurring in the medicinal plant Centella asiatica, with a molecular formula of C30H48O6 and a molecular weight of 504.70. It is supplied as a white to off white crystalline powder with a purity of 98.0% or higher by HPLC, and is soluble in ethanol, methanol and DMSO, while being sparingly soluble in water.
As one of the major bioactive aglycones of Centella asiatica, it is well recognized for its anti-inflammatory, antioxidant and skin repairing properties, and it actively promotes collagen synthesis and wound healing. These characteristics make madecassic acid a highly valued ingredient in cosmetic formulations for anti-aging, scar improvement and skin regeneration, as well as in pharmaceutical preparations for dermatological care and in health supplement products.
Madecassic acid Chemical Properties
| Melting point | 270°C (dec.) |
| Boiling point | 641.7±55.0 °C(Predicted) |
| density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Sparingly), Methanol (Slightly, Heated) |
| pka | 4.63±0.70(Predicted) |
| form | Solid |
| color | White to off white |
| InChIKey | PRAUVHZJPXOEIF-MRQYELSVNA-N |
| LogP | 4.321 (est) |
| Hazard Codes | Xi |
| Safety Statements | 24/25 |
| HS Code | 29389090 |
Product Application of Madecassic Acid CAS#18449-41-7
Multiple in-vitro and living-organism experiments verify its wide-ranging bio-medical traits. It can ease inflammation triggered by collagen-induced arthritis, stimulate the growth of human fibroblast cells and serve for the prevention and remedy of hypertrophic scars and keloid lesions. This natural compound can also safeguard heart tissue against damage brought on by myocardial ischaemia-reperfusion.It delivers mood-lifting effects through lowering the activity of brain monoamine oxidase.
Moreover, this natural triterpenoid substance can be deployed for multiple laboratory-based analytical operations, including substance identification, quantitative content testing and diverse pharmacology-related experimental investigation.
