Products Description of 6-Bromo-2,3-dihydro-4H-chromen-4-one CAS#49660-57-3
6-Bromo-2,3-dihydro-4H-chromen-4-one, also known as 6-bromochroman-4-one, is a fused heterocyclic compound with molecular formula C₉H₇BrO₂ and molecular weight 227.05. It appears as white to orange to green crystalline powder. This substance is sparingly soluble in water and soluble in common polar organic solvents like dichloromethane, ethanol and tetrahydrofuran.
It features a reactive bromine substituent and chromanone ring structure, supporting cross-coupling and other derivatization reactions. High-purity grades are available for fine chemical and pharmaceutical research.
6-Bromo-2,3-dihydro-4H-chromen-4-one Chemical Properties
| Melting point | 77-83°C |
| Boiling point | 336.6±42.0 °C(Predicted) |
| density | 1.621±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | White to Orange to Green |
| InChIKey | PFLPVOXSUCCZDH-UHFFFAOYSA-N |
| CAS DataBase Reference | 49660-57-3(CAS DataBase Reference) |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
| HS Code | 2914390090 |
Product Application of 6-Bromo-2,3-dihydro-4H-chromen-4-one CAS#49660-57-3
6-Bromo-2,3-dihydro-4H-chromen-4-one serves as a privileged heterocyclic building block for pharmaceutical R&D. Its chromanone scaffold is widely used to construct bioactive molecules for anti-tumor, anti-inflammatory and antimicrobial candidate drugs. The aryl bromide group enables Suzuki coupling and other synthetic transformations to modify molecular structures for structure-activity relationship study.
It is also applied in the synthesis of natural product analogues with chromanone core. This intermediate is suitable for laboratory-scale research, pilot synthesis and custom fine chemical production for drug discovery and heterocyclic compound development.
